CBD – can·na·bi·di·ol:
a powerful compound found primarily in the flowers and leaves of the hemp plant. Known for supporting body and mind in various ways.
What is the Endocannabinoid System, or ECS?
Discovered in the late 1980s, the Endocannabinoid System, or ECS is a biological system found in all mammals, composed of endocannabinoids and cannabinoid receptors. ECS affects virtually every cell, muscle, organ and tissue in our body, and is critical in regulating a wide range of body processes, our nervous system, immune system, digestive system, endocrine glands, brain, heart, lungs, kidneys, liver, spleen, bones, muscles, blood vessels and cells, lymph cells, and fat cells.
The ECS is believed to have more cellular receptor sites than any other receptor system. The widespread distribution of these cannabinoid receptors shows just how important the ECS is to our overall bodily function and health.
What are Endocannabinoids?
Endocannabinoids are endogenous neurotransmitters that are produced by our bodies. They regulate neurotransmission and allow for feedback loops. Anandamide and 2-Arachidonoylglycerol (2-AG) are the two primary endocannabinoids.
What are Phytocannabinoids and how are they different than Endocannabinoids?
Phytocannabinoids are plant derivative compounds (primarily extracted from cannabis) that mimic the characteristics of the endocannabinoids. THC and Cannabidiol (CBD) are the two primary phytocannabinoids that mimic the endocannabinoids Anandamide and 2-AG, respectively. Both endocannabinoid and phytocannabinoids, collectively referred to as cannabinoids, bind to cannabinoid receptors that exist throughout the mammalian body.
What are cannabinoid receptors?
Our ECS includes two primary cell cannabinoid receptors, CB1 and CB2. While these receptors are found throughout the body, they tend to concentrate in certain areas. CB1 receptors are abundant in the brain, while CB2 receptors are more often found on immune cells, in the gastrointestinal tract, and in the peripheral nervous system.
The endocannabinoid Anandamide, as well the phytocannabinoid THC target CB1 receptors, predominantly found in the brain and nervous system, as well as in peripheral organs and tissues. The other main endocannabinoid 2-Arachidonoylglycerol (2-AG) and its own mimetic phytocannabinoid, CBD, are active at both CB1 and CB2 cannabinoid receptors.
Why is ECS important?
The ECS promotes homeostasis, or dynamic biological balance, in every cell, tissue, and organ, including the brain. Our ECS is responsible for overall health and wellness when properly functioning. Specifically, both 2-AG and CBD are involved in the regulation of immune system functions, inflammation, sleep, stress response, appetite, mood, memory and pain management.
Homeostasis, or dynamic balance, is the concept that most biological systems are actively regulated to maintain conditions within a narrow range. Conditions need to be just right for our cells to maintain optimum performance. The ECS is a vital molecular system for helping maintain homeostasis—the stronger our physiological ability to stay in homeostasis is, the more robust our capacity to be in homeostasis, the healthier we are.
Cannabinoids help coordinate and regulate how we feel and think by binding with the endocannabinoid system’s CB1 and CB2 receptors. Fitting like puzzle pieces, cannabinoids are designed to link together with the cannabinoid receptors.
WHAT ARE THE BENEFITS OF CBD OIL?
CBD oil is gaining in popularity daily due to the number of people using CBD as an alternative to many commercial products and finding results. In addition, many studies are demonstrating how this oil is naturally assisting in the healing process of many health conditions. This oil can be used orally or topically depending on what you are treating.
Here are the most common uses for CBD
Stress and Anxiety Relief
Seizures (Occurrence Reduction)
Post Workout Muscle Repair
These products are not FDA approved and we are not claiming that this oil can cure or treat any of the conditions mentioned below or on this website. Government owns patent on cannabinoids
The US government owns patent #6630507. This patent is not new, in fact it was applied for in 1999 and granted in 2003 to the US Department of Health and Human Services. To read a quick summary on what this patent contains please click on the link below.
This is the million dollar question: what can CBD be used for? Before we dive into some of the uses, we need to make clear the fact that CBD research is in its infancy, and there are only a handful of definitive CBD studies right now. Therefore, it would be highly irresponsible to suggest that CBD is definitely or directly linked to any of these potential applications. Right now, CBD usage is wide open, and people are self-treating for a wide variety of symptoms.
Pain and Inflammation Relief
One of the most highly researched potential applications of CBD right now is its analgesic effect. It’s likely that CBD disrupts pain receptors, paradoxically triggering release of dopamine and serotonin instead. There’s evidence to suggest that this can work even in patients for whom pharmaceutical options aren’t working, or for whom it isn’t safe to prescribe them.
One of the most popular reasons people purchase products on CBDfx.com, according to reviews and anecdotal user reports, is for anxiety relief. CBD has even been shown to counteract many of the effects of THC, including reduction of paranoia, stress, and anxiety. Several studies have already demonstrated measurable anxiety reduction from CBD usage based on biometric data while participants engaged in public speaking.
Via indirect agonism of 5-HT(1A), CBD has been shown to attenuate vomiting and nausea-related behavior according to a 2012 study. CBD indirectly activates autoreceptors in the dorsal raphe nucleus, which produces an anti-emetic (anti-nausea) effect. This can be an unspeakable relief for people who are experiencing nausea for a wide variety of reasons.
CBD is often discussed as part of a potential future treatment for schizophrenia and other forms of psychosis. The compound has been shown to induce a calming, anti-psychotic property in both humans and animals in more than one study.
Particularly when it comes to the cessation of eczema and acne, CBD oil (used as a topical treatment) is becoming increasingly popular. It’s thought that CBD’s anti-inflammatory potential could work synergistically with its positive effect on skin appearance and health.
CBD can have a sedative effect, particularly at higher doses. If you’ve ever suffered from insomnia or a condition that was keeping you from falling asleep, you know what a relief it can be to finally drift off for even a few hours.
What Are Benefits of CBD Oil?
Cannabidiol (CBD) is the most predominant cannabinoid in hemp, and has many beneficial properties.
In its patent (#6,630,507) titled CANNABINOIDS AS ANTIOXIDANTS AND NEUROPROTECTANTS, the U.S. federal government makes many impressive claims about CBD, stating that:
“Cannabinoids are potent antioxidants… they easily penetrate tissues giving them the ability to enter the central nervous system and brain.”
“Non-psychoactive cannabinoids such as CBD are particularly advantageous as they are non-toxic… and exhibit unique antioxidant properties without the undesirable effects of THC.”
“The antioxidant strength of CBD is significantly greater than that of either Vitamin C or Vitamin E.”
Our products contain only non-psychoactive cannabinoids. The primary psychotropic chemical in marijuana which alters human perception is THC. Meditonix CBD is derived from industrial hemp and contains no THC. Our products will not produce the qualitative effects commonly referred to as a “high” which is often associated with the consumption of products derived from marijuana.
Is CBD Legal?
Yes — although CBD comes from the cannabis plant family like its intoxicating cousin compound THC, you will not feel a “high” or psychoactive effect from CBD. Although there are tiny trace amounts of THC in most CBD products, the amount is so low that it is functionally impossible to get intoxicated from it. Therefore, CBD is legal to purchase and own across the United States. You can shop for CBD products with full confidence (and at CBDfx, we provide unique batch lab reports so that you can see exactly what you’re putting in your body, and in what proportion).
Is it legal? Some 47 states as well as Puerto Rico and Washington, D.C. have passed laws allowing the use of CBD to some extent, according to marijuana advocacy organization NORML. After the 2018 Farm Bill goes into effect it will be completely legal in all 50 states.
WHAT DOES THE FARM BILL HAVE TO DO WITH CBD? — The Farm Bill amends the Agricultural Marketing Act of 1946, redefining the legal definition of the word “hemp” to include hemp-derived products, including cannabinoids like CBD. Here’s the new definition, with emphasis added:
The term hemp means the plant Cannabis sativa L. and any part of that plant, including the seeds thereof and all derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers, whether growing or not, with a delta-9 tetrahydrocannabinol concentration of not more than 0.3 percent on a dry weight basis.
It also amends the Controlled Substances Act of 1970 to clarify that the term “marihuana” does not include this new definition of hemp.
In the past, the DEA had argued that all cannabis extracts, whether derived from hemp or high-THC strains, were Schedule 1 substances. But this law clearly states that hemp and hemp derivatives like CBD are not controlled substances. And this means that the DEA can no longer claim any jurisdiction over hemp-derived CBD.
But that doesn’t mean that hemp and CBD won’t be regulated. The difference is that the authority to make rules about these crops and products will shift to the USDA, the FDA, and the states.
Health Benefits of CBD
Transdermal cannabidiol reduces inflammation
17 CBD Clinical Studies
Best Site – All whitepapers in one place and cited